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Further study is needed to determine the full effect of WBV on spasticity in persons with different levels and completeness of SCI, as well as the functional effects of these changes in spasticity.

Your surgeon may select to use a metal plate that is screwed into the front of the vertebra to help the healing process.

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Although the literature is not sufficient to recommend baclofen as a first-line agent for the treatment of alcohol dependence, clinicians should maintain awareness of new and novel uses of medications for alcohol dependence.

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Baclofen is used in the treatment of muscle spasm; alcohol withdrawal; cervical dystonia; spasticity; chronic spasticity (and ), and belongs to the drug class skeletal muscle relaxants.

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When prescribed for alcohol dependence, side effects associated with baclofen included fatigue, sleepiness, insomnia, dizziness, paraesthesia, nausea, vomiting, sensory alterations, sexual changes (decrease or increase of libido), various forms of pain (including headache), bowel disorder (diarrhea or constipation), dysphoria, weight loss or gain, and memory loss, among others side effects.

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Topiramate (eg, Topamax); Baclofen (eg, Lioresal); prednisone; Clonidine (eg, Catapres-TTS).

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Since ITB may be appropriate for a broad range of disabilities, from ambulatory to vegetative states, treatment and functional goals must be individualized, clearly understood, and agreed upon by the patient, family, caregivers, and care-provider team before treatment begins.

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Racemic baclofen (mixture of arbaclofen and esbaclofen) is approved by the FDA to treat spasticity and stiff muscles due to cerebral palsy or other forms of brain or spinal cord injury, but arbaclofen, the more active form of baclofen, is not FDA approved.

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Those on an individual dosing schedule are usually started on 40 mg of Baclofen per day, which is increased as necessary to help manage your condition effectively.

Intrathecal baclofen therapy for spastic hypertonia.

Objective: To report treatment of spasticity in a spinal cord-injured person with intrathecal morphine after the person developed tolerance to intrathecal baclofen.

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Doses used in this patient population for long term infusion are generally lower than those required for patients with spasticity of spinal cord origin.

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Limited data are available from well-conducted trials, though numerous trials are underway or recently completed with a goal of evaluating baclofen for maintenance of abstinence in alcohol-dependent patients.

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Examples of these medications include baclofen, tizanidine, clonidine, benzodiazepines such as diazepam or clonazipam, gabapentin and dantrolene.

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GABA released by some nerves causes the activity of other nerves to decrease.

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